The Effect of Swimming Training with Cinnamon Extract on Hematological Factors in Diabetic Rats

Objective: Diabetes is one of the most common metabolic diseases which can lead to cardiovascular disorders. The purpose of this study was to evaluate the effect of swimming training with cinnamon extract on hematological factors in diabetic rats. Materials and Methods: 60 diabetic rats selected and divided into six group of: (1) control, (2) swimming training, (3) 60mg / kg of cinnamon, (4) 40 mg / kg of cinnamon, (5) swimming training with 60mg / kg cinnamon and (6) swimming training with 40 mg / kg cinnamon. Groups 2, 5 and 6 (five sessions per week for eight weeks) swam for 10 minutes and 30 minutes in the first two weeks and in the remaining six weeks respectively. Groups 3, 4, 5 and 6 received the prescribed amount of cinnamon extract daily. For statistical analysis of data used one way analysis variance and Tukey post hoc test (P≤ 0.05). Results: Swimming training, 40 and 60 mg/kg cinnamon extract, swimming training with 40 and 60 mg/kg cinnamon extract have significant effect on reduction of HbA1c (P-value:0.001) and have no significant effect on WBC (P-value:0.28), RBC (P-value:0.66) and platelets (P-value:0.07) in diabetic rats and 60 mg/kg cinnamon extract is more effective than 40 mg/kg cinnamon extract (P-value:0.001) and swimming training (P-value:0.007) in reduction of  HbA1c in diabetic rats. Conclusion: Swimming training and cinnamon extract can improve HbA1c in diabetic rats.